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Hydrochlorothiazide, hctz; spironolactone moderate olanzapine may induce orthostatic hypotension and thus enhance the effects of antihypertensive agents.
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In considering the use of lisinopril and hydrochlorothiazide tablets, it should be noted that ace inhibitors have been associated with a higher rate of angioedema in black than in non-black patients.
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following oral administration, plasma hydrochlorothiazide concentrations decline biexponentially, with a mean distribution half-life of about 2 hours and an elimination half-life of about 10 hours.